Chitinase-like protein 1

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August undefined, 2024

WebBecause of their amino acid sequence similarities, human chitinases are classified into the 18 glycosyl hydrolase (GH18) family. 2, –, 4 The human protein family encodes 2 true chitinases, chitotriosidase (CHIT1), and acidic mammalian chitinase (AMCase), and several CLPs: chitinase-3-like 1 (CHI3L1), chitinase-3-like 2 (CHI3L2), oviductin ... WebChitinase-3-like protein 1 (CHI3L1), also known as YKL-40, is a secreted glycoprotein that is approximately 40kDa in size that in humans is encoded by the CHI3L1 gene. The name YKL-40 is derived from the three N …

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WebChitinase 3-like 1 (CHI3L1), also called BRP39 in mouse or YKL-40 in humans, is a 39 kDa glycoprotein member of the glycosyl hydrolase 18 family although it does not show chitotriosidase activity. CHI3L1 is expressed by articular chondrocytes, synovial cells, activated monocyte-derived macrophages, neutrophils, endothelial cells, vascular ... WebJan 25, 2024 · Acidic chitinase (Chia) has been implicated in asthma, allergic inflammations, and food processing. We have purified Chia enzymes with striking acid stability and protease resistance from chicken and pig stomach tissues using a chitin column and 8 M urea (urea-Chia). Here, we report that acetic acid is a suitable agent for native … shannon ortega

Role of breast regression protein-39 in the pathogenesis of …

WebChitinase-3-Like Protein 1. YKL-40, a 40 kDa plasma protein, is the best-known protein from the CLPs group. YKL-40 lacks chitinolytic activity due to the mutation of glutamic acid to leucine in the chitinase-3-like catalytic domain. 27 The expression of YKL-40 was found in different mammalian organs and tissues (ie, ... WebPTHR22595:SF176 CHITINASE-LIKE PROTEIN 2 1 hit; PTHR22595 CHITINASE-RELATED 1 hit; PIRSF. PIRSF001060 Endochitinase 1 hit; Pfam. View protein in Pfam; … pomegranate hand wash

Chil1 MGI Mouse Gene Detail - MGI:1340899 - chitinase-like 1

Roles of chitinase 3-like 1 in the development of cancer ...

WebThe Quantikine Human CHI3L1 Immunoassay is a 4.5 hour solid phase ELISA designed to measure CHI3L1 in cell culture supernates, serum, plasma, and urine. It contains NS0 … WebJan 1, 2024 · Protein S100-A9, Protein S100-A8, Chitinase-3-like protein 1, Haptoglobin, Integrin beta-2, and Chloride intracellular channel protein 1 were more abundant in milk-derived EVs for clinical mastitis. The data obtained in this study expanded the repertoire of bovine milk-derived proteins and conduced more attention to the function. shannon orso agentWebMar 28, 2024 · chitinase-3-like protein 1, CGP-39, GP-39, YKL-40, breast regression protein 39, cartilage glycoprotein 39, chitinase 3-like 1. GeneRIFs: Gene References Into Functions. Multi-omics profiling reveals Chitinase-3-like protein 1 as a key mediator in the crosstalk between sarcopenia and liver cancer. shannon orsini edmonton

"WebChitinase 3-like 1. Chitinase 3-like 1 (CHI3L1), also known as YKL-40, is a secreted glycoprotein member of the glycoside hydrolase 18 chitinase family that targets chitin but lacks enzymatic activity (Renkema et al., 1998). Although its physiologic function remains unknown, recent studies support a clear prognostic role for CHI3L1 in MS. " - Chitinase-like protein 1

Chitinase-like protein 1

Frontiers Chitinase-3 like-protein-1, matrix metalloproteinase -9 …

WebAltogether, 14 chitinase-related genes (12 chitinase genes and 2 IDGFs) encoding 17 proteins were identified from the genome sequence of Ae. albopictus (Table (Table1). 1). These identified putative chitinase-like genes were assigned gene numbers according to the previously identified members of the other insect chitinase-like gene family to ... WebChitinase-3-like protein 1 (YKL-40, also named human cartilage glycoprotein 39) is a mammalian glycoprotein related in sequence to family 18 of bacterial and fungal …

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WebFeb 14, 2024 · NM_001374626.1 → NP_001361555.1 chitinase-3-like protein 1 isoform 2 precursor. Status: VALIDATED. Source sequence(s) AC137104 Consensus CDS CCDS87878.1 Related ENSMUSP00000119205.2, ENSMUST00000156873.8 Conserved Domains (1) summary cd02872 Location: 22 → 378 WebChitinase 3-like 1. Chitinase 3-like 1 (CHI3L1), also known as YKL-40, is a secreted glycoprotein member of the glycoside hydrolase 18 chitinase family that targets chitin …

WebApr 6, 2024 · IntroductionPositive intracranial arterial remodelling is a dilated lesion of the large intracranial vessels; however, its pathogenesis is currently unknown. Some studies … WebFeb 19, 2024 · Systemic sclerosis (SSc) is an autoimmune disease with completely undefined etiology and treatment difficulties. The expression of both protein coding and …

WebDiagnosis of cardiac surgery-associated acute kidney injury: differential roles of creatinine, chitinase 3-like protein 1 and neutrophil gelatinase-associated lipocalin: a prospective … WebChitinase 3-like 1 (CHI3L1) is a secreted glycoprotein that mediates inflammation, macrophage polarization, apoptosis, and carcinogenesis. The expression of CHI3L1 is strongly increased by various inflammatory and immunological conditions, including rheumatoid arthritis, multiple sclerosis, Alzheimer's disease, and several cancers.

WebFollowing re-crystallization at neutral pH, the crystals were identified as the chitinase-like protein Ym1, expressed in organs of the lymphoreticular system, the lung, and distal stomach . Co-expression of Ym1 with Mac-1 and scavenger receptor pinpoints macrophages as its main producer .

WebChitinase domain-containing protein 1 (CHID1) is a highly conserved protein of unknown function located on the short (p) arm of chromosome 11 near the telomere. [5] The … pomegranate hospitalityWebThe exaggerated expression of chitinase-like protein YKL-40, the human homologue of breast regression protein-39 (BRP-39), was reported in a number of diseases, including chronic obstructive pulmonary disease (COPD). However, the in vivo roles of YKL-40 in normal physiology or in the pathogenesis of … shannon ort attorneyWebMar 21, 2024 · CHIT1 (Chitinase 1) is a Protein Coding gene. Diseases associated with CHIT1 include Chitotriosidase Deficiency and Gaucher's Disease.Among its related pathways are Digestion and absorption and Innate Immune System.Gene Ontology (GO) annotations related to this gene include hydrolase activity, hydrolyzing O-glycosyl … shannon orthodonticsWebJohansen and Carretta et al. found that COS exerted their anti-tumorigenic effects through the inhibition of YKL-40 (also known as chitinase-3-like 1 or Chi3L1), which is a conserved, secreted chitinase-like protein (CLP) found in elevated levels in many diseases, including cancer [126,127]. shannon orr mdWebFeb 19, 2024 · Systemic sclerosis (SSc) is an autoimmune disease with completely undefined etiology and treatment difficulties. The expression of both protein coding and non-coding RNAs is dysregulated during disease development. We aimed to examine a possible regulatory axis implemented in the control of chitinase-3 like protein 1 … shannon orthodontics grandvilleWebAfter the successful colonization of rice roots by S. indica, both the rice blast disease and bakanae disease were significantly reduced. Interestingly, the purified SiChi could … pomegranate hospitality new orleansWebBackground: Chitinase 3-like protein 1 (CHI3L1) is most likely a malignant tumor metastasis-associated gene. However, the functions of CHI3L1 in colon cancer cell proliferation and its cetuximab sensitivity are still unclear. We aimed to investigate the mechanism of CHI3L1 in promoting colon cancer cell proliferation and its sensitivity to … shannon orthodontics plainwell mi