WebJan 25, 2024 · Wang et al. (2006) noted that E2A (TCF3; 147141) homodimers are essential for early B-cell development, whereas HEB/E2A heterodimers are dominant during T-cell development. By screening a mouse pro-T-cell cDNA library, followed by database analysis, they identified a novel HEB variant, which they termed HEBAlt. WebFeb 14, 2014 · Rearrangements of TCF3 (E2A) occur in <5% of childhood B-cell precursor acute lymphoblastic leukemia (BCP-ALL) cases. 1 In 90–95% of these rearranged cases, TCF3 (chromosome 19p13) is fused to ...
CytoCell E2A (TCF3)/PBX1 Translocation, Dual …
WebFeb 11, 2024 · Seventy percent of the world’s internet traffic passes through all of that fiber. That’s why Ashburn is known as Data Center Alley. The Silicon Valley of the east. The cloud capital of the ... WebMar 21, 2024 · TCF3 (Transcription Factor 3) is a Protein Coding gene. Diseases associated with TCF3 include Agammaglobulinemia 8B, Autosomal Recessive and Agammaglobulinemia 8A, Autosomal Dominant.Among its related pathways are Gene … fish protein isolate market
小鼠内皮型一氧化氮合成酶（eNOS）Elisa试剂盒eNOS ELISA Kit
Transcription factor 3 (E2A immunoglobulin enhancer-binding factors E12/E47), also known as TCF3, is a protein that in humans is encoded by the TCF3 gene. TCF3 has been shown to directly enhance Hes1 (a well-known target of Notch signaling) expression. See more This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. The 9aaTAD transactivation domains of E proteins and MLL are very similar and both bind to the KIX domain of … See more Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that … See more TCF3 has been shown to interact with: • CBFA2T3, • CREBBP, • ELK3, See more • LeBrun DP (May 2003). "E2A basic helix-loop-helix transcription factors in human leukemia". Frontiers in Bioscience. 8 (1–3): s206–22. doi:10.2741/1030. PMID 12700034 See more WebThe Tcf3-CBD forms an elongated structure with three binding modules that runs antiparallel to beta-catenin along the positively charged groove formed by the armadillo repeats . These results suggest a novel mechanism for regulating the dimerization status and DNA binding properties of E2A HLH transcription factors [11] . WebThe Dulles Technology Corridor is a descriptive term for a string of communities that lie along and between Virginia State Route 267 (the Dulles Toll Road and Dulles Greenway), and Virginia State Route 7 (Leesburg Pike and Harry Byrd Highway). It especially … c and i show hardware